Molecular Dynamics Simulation of the alpha-Helix to beta- Sheet Transition in Coiled Protein Filaments: Evidence for a Critical Filament Length Scale Citation
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Molecular dynamics simulation of the α-helix to β-sheet transition in coiled protein filaments: evidence for a critical filament length scale.
The alpha-helix to beta-sheet transition (α-β transition) is a universal deformation mechanism in alpha-helix rich protein materials such as wool, hair, hoof, and cellular proteins. Through a combination of molecular and theoretical modeling, we examine the behavior of alpha-helical coiled-coil proteins with varying lengths under stretch. We find that the occurrence of the α-β transition is con...
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تاریخ انتشار 2010